The Role of the Extrafibrillar Volume on the Mechanical Properties of Molecular Models of Mineralized Bone Microfibrils

• Published in: ACS biomaterials science & engineering Vol. 9; no. 1; pp. 230 - 245
• Main Authors: de Alcântara, Amadeus C. S., Felix, Levi C., Galvão, Douglas S., Sollero, Paulo, Skaf, Munir S.
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 09.01.2023
• Subjects: Animals; Bone and Bones; Microfibrils; Minerals; Modeling and Informatics Tools; Models, Molecular; Water; mineralized collagen fibril; bone nanomechanics; collagen fiber; molecular dynamics; extrafibrillar volume; microfibrils

Bones are responsible for body support, structure, motion, and several other functions that enable and facilitate life for many different animal species. They exhibit a complex network of distinct physical structures and mechanical properties, which ultimately depend on the fraction of their primary...