Peptide Self-Assembly Controlled Photoligation of Polymers

• Published in: Journal of the American Chemical Society Vol. 145; no. 29; pp. 15981 - 15989
• Main Authors: Richardson, Bailey J., Zhang, Chao, Rauthe, Pascal, Unterreiner, Andreas-Neil, Golberg, Dmitri V., Poad, Berwyck L. J., Frisch, Hendrik
• Format: Journal Article
• Language: English
• Published: WASHINGTON American Chemical Society 26.07.2023; Amer Chemical Soc
• Subjects: amino acids; catalysts; catalytic activity; Chemistry; Chemistry, Multidisciplinary; dimethylformamide; electrostatic interactions; hydrophilicity; hydrophobicity; irradiation; oxygen; peptides; Physical Sciences; polymers; protonation; Science & Technology; REVERSIBLE 2+2 PHOTOCYCLOADDITION; ENERGY-TRANSFER; MICELLES; DNA; AGGREGATION; AMPHIPHILE NANOFIBERS

Highly efficient chemical ligations that operate in water under mild conditions are the foundation of bioorthogonal chemistry. However, the toolbox of suitable reactions is limited. Conventional approaches to expand this toolbox aim at altering the inherent reactivity of functional groups to design...