Precise Tuning of the D‑Band Center of Dual-Atomic Enzymes for Catalytic Therapy

• Published in: Journal of the American Chemical Society Vol. 146; no. 14; pp. 10023 - 10031
• Main Authors: Zeng, Ruijin, Gao, Qian, Xiao, Limei, Wang, Weijun, Gu, Yu, Huang, Hengshuo, Tan, Yingjun, Tang, Dianping, Guo, Shaojun
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 10.04.2024
• Subjects: Adsorption; Carbon; Catalysis; catalytic activity; dissociation; enzymes; Humans; Hydrogen Peroxide; Neoplasms; photothermotherapy; synergism; Tumor Microenvironment

Single-atom nanozyme-based catalytic therapy is of great interest in the field of tumor catalytic therapy; however, their development suffers from the low affinity of nanozymes to the substrates (H2O2 or O2), leading to deficient catalytic activity in the tumor microenvironment. Herein, we report a...