Hybrid Cornea: Cell Laden Hydrogel Incorporated Decellularized Matrix

• Published in: ACS biomaterials science & engineering Vol. 6; no. 1; pp. 122 - 133
• Main Authors: Uyanıklar, Merve, Günal, Gülçin, Tevlek, Atakan, Hosseinian, Pezhman, Aydin, Halil Murat
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 13.01.2020
• Subjects: Animals; Cattle; Cornea; Extracellular Matrix; Gelatin; Hydrogels; Methacrylates; photopolymerization; decellularization; cornea; gelatin methacrylate (GelMA); transparency

The decellularization protocols applied on the corneal stromal constructs in the literature usually fail to provide a corneal matrix with sufficient mechanical and optical properties since they alter the extracellular matrix (ECM) microstructure. In this study, to overcome these limitations, a hybri...