Straightforward Access to a Great Diversity of Complex Biorelevant γ‑Lactams Thanks to a Tunable Cascade Multicomponent Process

This reviews surveys the preparation of a great diversity of complex biorelevant γ-lactam backbones thanks to scalable copper­(I)-catalyzed cascade multicomponent processes.

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Bibliographic Details
Published inOrganic process research & development Vol. 24; no. 5; pp. 606 - 614
Main Authors Mardjan, Muhammad Idham Darussalam, Mayooufi, Atef, Parrain, Jean-Luc, Thibonnet, Jérôme, Commeiras, Laurent
Format Journal Article
LanguageEnglish
Published American Chemical Society 15.05.2020
Subjects
Chemical Sciences
Organic chemistry
lactams
copper catalysis
γ-hydroxybutyrolactams
heterocyclic compounds
multicomponent reaction
spirolactams
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Summary:This reviews surveys the preparation of a great diversity of complex biorelevant γ-lactam backbones thanks to scalable copper­(I)-catalyzed cascade multicomponent processes.
ISSN:1083-6160
1520-586X
DOI:10.1021/acs.oprd.9b00438