Role of Metabolic Activation in 8‑Epidiosbulbin E Acetate-Induced Liver Injury: Mechanism of Action of the Hepatotoxic Furanoid - Lin, Dongju; Li, Weiwei; Peng, Ying; Jiang, Chunfeng; Xu, Youjun; Gao, Huiyuan; Zheng, Jiang (Chemical research in toxicology, 2016)
Keywords: Activation, Metabolic - drug effects; Animals; Chemical and Drug Induced Liver Injury - etiology; Chemical and Drug Induced Liver Injury - metabolism; Chemical and Drug Induced Liver Injury - pathology; Chemical and Drug Induced Liver Injury - prevention & control; Cytochrome P-450 Enzyme System - metabolism; Diterpenes - administration & dosage; Diterpenes - metabolism; Diterpenes - toxicity; Dose-Response Relationship, Drug; Ketoconazole - administration & dosage; Ketoconazole - pharmacology; Male; Mice; Mice, Inbred Strains; Molecular Structure; Time Factors