Mechanism of Inhibition of the Reproduction of SARS-CoV‑2 and Ebola Viruses by Remdesivir - Wang, Jimin; Reiss, Krystle; Shi, Yuanjun; Lolis, Elias; Lisi, George P; Batista, Victor S (Biochemistry (Easton), 2021)
Keywords: Adenosine Monophosphate - analogs & derivatives; Adenosine Monophosphate - genetics; Adenosine Monophosphate - metabolism; Alanine - analogs & derivatives; Alanine - genetics; Alanine - metabolism; antiviral agents; Antiviral Agents - metabolism; Base Pairing; cell lines; chemistry; Coronavirus RNA-Dependent RNA Polymerase - antagonists & inhibitors; Coronavirus RNA-Dependent RNA Polymerase - genetics; Coronavirus RNA-Dependent RNA Polymerase - metabolism; Ebolavirus; Ebolavirus - drug effects; Enzyme Inhibitors - metabolism; exoribonucleases; Models, Molecular; nucleosides; Protein Biosynthesis - drug effects; protein synthesis; reproduction; RNA - genetics; RNA - metabolism; RNA, Messenger - genetics; RNA, Messenger - metabolism; RNA, Viral - genetics; RNA, Viral - metabolism; SARS-CoV-2 - drug effects; Severe acute respiratory syndrome coronavirus 2; Virus Replication - drug effects