Stereoselective Alkene Isomerization over One Position

• Published in: Journal of the American Chemical Society Vol. 134; no. 25; pp. 10357 - 10360
• Main Authors: Larsen, Casey R, Grotjahn, Douglas B
• Format: Journal Article
• Language: English
• Published: WASHINGTON American Chemical Society 27.06.2012; Amer Chemical Soc
• Subjects: ambient temperature; catalysts; Chemistry; Chemistry, Multidisciplinary; isomerization; Physical Sciences; Science & Technology; stereochemistry; CARBENE; ETHERS; ALLYLIC ALCOHOLS; DOUBLE-BOND MIGRATION; COMPLEXES; IRIDIUM-CATALYZED ISOMERIZATION; BIFUNCTIONAL CATALYST; O-ALLYL; RUTHENIUM; REDOX ISOMERIZATION

Although controlling both the position of the double bond and E:Z selectivity in alkene isomerization is difficult, 1 is a very efficient catalyst for selective mono-isomerization of a variety of multifunctional alkenes to afford >99.5% E-products. Many reactions are complete within 10 min at roo...