Electrophilic Aromatic Substitution: New Insights into an Old Class of Reactions

• Published in: Accounts of chemical research Vol. 49; no. 6; pp. 1191 - 1199
• Main Authors: Galabov, Boris, Nalbantova, Didi, Schleyer, Paul von R, Schaefer, Henry F
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 21.06.2016

The classic SEAr mechanism of electrophilic aromatic substitution (EAS) reactions described in textbooks, monographs, and reviews comprises the obligatory formation of arenium ion intermediates (σ complexes) in a two-stage process. Our findings from several studies of EAS reactions challenge the gen...