Methodology for the Absolute Configuration Determination of Epoxythymols Using the Constituents of Ageratina glabrata

• Published in: Journal of natural products (Washington, D.C.) Vol. 81; no. 1; pp. 63 - 71
• Main Authors: Arreaga-González, Héctor M, Pardo-Novoa, Julio C, del Río, Rosa E, Rodríguez-García, Gabriela, Torres-Valencia, J. Martín, Manríquez-Torres, J. Jesús, Cerda-García-Rojas, Carlos M, Joseph-Nathan, Pedro, Gómez-Hurtado, Mario A
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society and American Society of Pharmacognosy 26.01.2018

A methodology to determine the enantiomeric excess and the absolute configuration (AC) of natural epoxythymols was developed and tested using five constituents of Ageratina glabrata. The methodology is based on enantiomeric purity determination employing 1,1′-bi-2-naphthol (BINOL) as a chiral solvat...