CuATSM Protects Against the In Vitro Cytotoxicity of Wild-Type-Like Copper–Zinc Superoxide Dismutase Mutants but not Mutants That Disrupt Metal Binding - Farrawell, Natalie E; Yerbury, Maddison R; Plotkin, Steven S; McAlary, Luke; Yerbury, Justin J (ACS chemical neuroscience, 2019)
Keywords: Amyotrophic Lateral Sclerosis - drug therapy; Amyotrophic Lateral Sclerosis - genetics; Animals; Chelating Agents - pharmacology; Copper - metabolism; Humans; Mice; Mutation - genetics; Neurons - drug effects; Neurons - metabolism; Protective Agents - pharmacology; Superoxide Dismutase - genetics; Superoxide Dismutase - metabolism; Zinc - metabolism; ALS; copper; CuATSM; protein aggregation; SOD1