Antiparasitic Activity of Two Natural Terpenes from Salvia cuspidata against Leishmania amazonensis

• Published in: Journal of natural products (Washington, D.C.) Vol. 86; no. 4; pp. 797 - 803
• Main Authors: Troncoso, Mariana Elizabeth, Germanó, María José, Arrieta, Victoria J., García Bustos, María Fernanda, Cifuente, Diego, Cargnelutti, Diego E., Lozano, Esteban S.
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society and American Society of Pharmacognosy 28.04.2023
• Subjects: Animals; Antiparasitic Agents - pharmacology; Antiprotozoal Agents - pharmacology; Antiprotozoal Agents - therapeutic use; Leishmania; Leishmania mexicana; Leishmaniasis, Cutaneous - drug therapy; Mice; Mice, Inbred BALB C; Salvia; Terpenes - pharmacology

Leishmaniasis is a neglected disease caused by flagellated parasites of the Leishmania genus affecting more than 10 million people worldwide. Current treatments for leishmaniasis involve the administration of poorly tolerated drugs with toxic side effects in patients. There is an imperative necessit...