Observations of Tunable Resistive Pulse Sensing for Exosome Analysis: Improving System Sensitivity and Stability

• Published in: Langmuir Vol. 31; no. 23; pp. 6577 - 6587
• Main Authors: Anderson, Will, Lane, Rebecca, Korbie, Darren, Trau, Matt
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 16.06.2015
• Subjects: Cryoelectron Microscopy; Electrochemical Techniques; Exosomes - ultrastructure; Membranes, Artificial; Nanopores; Organelle Size; Porosity; Sensitivity and Specificity

Size distribution and concentration measurements of exosomes are essential when investigating their cellular function and uptake. Recently, a particle size distribution and concentration measurement platform known as tunable resistive pulse sensing (TRPS) has seen increased use for the characterizat...