An Intelligent DNA Nanorobot with in Vitro Enhanced Protein Lysosomal Degradation of HER2 - Ma, Wenjuan; Zhan, Yuxi; Zhang, Yuxin; Shao, Xiaoru; Xie, Xueping; Mao, Chenchen; Cui, Weitong; Li, Qian; Shi, Jiye; Li, Jiang; Fan, Chunhai; Lin, Yunfeng (Nano letters, 2019)
Keywords: Animals; Aptamers, Nucleotide - chemistry; Aptamers, Nucleotide - pharmacology; Breast Neoplasms - drug therapy; Breast Neoplasms - metabolism; Breast Neoplasms - pathology; DNA - chemistry; DNA - pharmacology; Drug Delivery Systems; Endocytosis - drug effects; Female; Humans; Lysosomes - metabolism; Lysosomes - pathology; MCF-7 Cells; Mice; Mice, Nude; Proteolysis - drug effects; Receptor, ErbB-2 - metabolism; Robotics; Xenograft Model Antitumor Assays; breast cancer; DNA nanorobot; HER2; framework nucleic acids; aptamer; lysosome