A Photostable AIE Luminogen for Specific Mitochondrial Imaging and Tracking

• Published in: Journal of the American Chemical Society Vol. 135; no. 1; pp. 62 - 65
• Main Authors: Leung, Chris Wai Tung, Hong, Yuning, Chen, Sijie, Zhao, Engui, Lam, Jacky Wing Yip, Tang, Ben Zhong
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 09.01.2013
• Subjects: apoptosis; Ethylenes - chemistry; fluorescent dyes; Fluorescent Dyes - chemistry; HeLa Cells; Humans; image analysis; mitochondria; Mitochondria - chemistry; Molecular Structure; Organophosphorus Compounds - chemistry; Photochemical Processes; photostability

Tracking the dynamics of mitochondrial morphology has attracted much research interest because of its involvement in early stage apoptosis and degenerative conditions. To follow this process, highly specific and photostable fluorescent probes are in demand. Commercially available mitochondria tracke...