Recent Progress toward the Construction of Axially Chiral Molecules Catalyzed by an N‑heterocyclic Carbene

• Published in: ACS catalysis Vol. 11; no. 20; pp. 12520 - 12531
• Main Authors: Wang, Jiaming, Zhao, Changgui, Wang, Jian
• Format: Journal Article
• Language: English
• Published: American Chemical Society 15.10.2021
• Subjects: N-heterocyclic carbene; axial chirality; organocatalysis; asymmetric synthesis; atroposelective annulation

Axial chirality widely exists in natural products, pharmaceutical compounds, and other functional molecules; these axially chiral compounds also find wide utility as catalysts or ligands in organic synthetic chemistry. Nevertheless, whereas significant progress has been made toward the synthesis of...