Functional Evaluation of the π‑Helix in the NAD(P)H:FMN Reductase of the Alkanesulfonate Monooxygenase System

• Published in: Biochemistry (Easton) Vol. 57; no. 30; pp. 4469 - 4477
• Main Authors: Musila, Jonathan M, L. Forbes, Dianna, Ellis, Holly R
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 31.07.2018

A subgroup of enzymes in the NAD­(P)­H:FMN reductase family is comprised of flavin reductases from two-component monooxygenase systems. The diverging structural feature in these FMN reductases is a π-helix centrally located at the tetramer interface that is generated by the insertion of an amino aci...