Phomopsols A and B from the Mangrove Endophytic Fungus Phomopsis sp. xy21: Structures, Neuroprotective Effects, and Biogenetic Relationships

• Published in: Organic letters Vol. 21; no. 19; pp. 7919 - 7922
• Main Authors: Li, Wan-Shan, Hu, Han-Bo, Huang, Zhong-Hui, Yan, Ren-Jie, Tian, Li-Wen, Wu, Jun
• Format: Journal Article
• Language: English
• Published: WASHINGTON American Chemical Society 04.10.2019; Amer Chemical Soc
• Subjects: Chemistry; Chemistry, Organic; Physical Sciences; Science & Technology; RHAZINILAM; ALKALOIDS

A polyketide-derived alkaloid featuring a unique 3,4-dihydro-2H-indeno­[1,2-b]­pyridine 1-oxide motif, named phomopsol A (1), and a highly oxidized polyketide containing a new 3,5-dihydro-2H-2,5-methanobenzo­[e]­[1,4]­dioxepine moiety, named phomopsol B (2), were isolated from the Thai mangrove endo...