Neural Evidence for Enhanced Error Detection in Major Depressive Disorder

• Published in: The American journal of psychiatry Vol. 164; no. 4; pp. 608 - 616
• Main Authors: Chiu, Pearl H., Deldin, Patricia J.
• Format: Journal Article
• Language: English
• Published: Washington, DC American Psychiatric Association 01.04.2007
• Subjects: Adult; Adult and adolescent clinical studies; Biological and medical sciences; Brain; Choice Behavior - physiology; Cues; Depression; Depressive Disorder, Major - diagnosis; Depressive Disorder, Major - etiology; Depressive Disorder, Major - physiopathology; Evoked Potentials - physiology; Feedback - physiology; Female; Gyrus Cinguli - physiopathology; Head injuries; Health facilities; Humans; Male; Medical sciences; Mental depression; Mood disorders; Motivation; Psychology. Psychoanalysis. Psychiatry; Psychomotor Performance - physiology; Psychopathology. Psychiatry; Reward; Studies; Task Performance and Analysis; Token Economy; Mood disorder; Error detection; Depression

Objective: Anomalies in error processing have been implicated in the etiology and maintenance of major depressive disorder. In particular, depressed individuals exhibit heightened sensitivity to error-related information and negative environmental cues, along with reduced responsivity to positive re...