Integrated Microfluidic Device for Functional Secretory Immunophenotyping of Immune Cells

• Published in: ACS sensors Vol. 5; no. 2; pp. 353 - 361
• Main Authors: Rodriguez-Moncayo, Roberto, Jimenez-Valdes, Rocio Jimena, Gonzalez-Suarez, Alan Mauricio, Garcia-Cordero, Jose Luis
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 28.02.2020
• Subjects: Humans; Immunoassay - methods; Immunophenotyping - methods; Microfluidics - methods; immune cells; MITOMI; single cells; microfluidic immunoassays; fluorescence biosensors; cytokine secretion

Integrated platforms for automatic assessment of cellular functional secretory immunophenotyping could have a widespread use in the diagnosis, real-time monitoring, and therapy evaluation of several pathologies. We present a microfluidic platform with integrated biosensors and culture chambers to me...