Enzymatic Recontouring of Auricular Cartilage in a Rabbit Model

• Published in: Archives of facial plastic surgery Vol. 7; no. 2; pp. 104 - 110
• Main Authors: Massengill, Phillip L, Goco, Paulino E, Norlund, L. Layne, Muir-Padilla, Jeanne
• Format: Journal Article
• Language: English
• Published: United States American Medical Association 01.03.2005
• Subjects: Animals; Cartilage; Chi-Square Distribution; Ear Cartilage - surgery; Ear Deformities, Acquired - drug therapy; Ear, External - surgery; Ears & hearing; Enzymes; Hyaluronoglucosaminidase - administration & dosage; Hyaluronoglucosaminidase - pharmacology; Injections, Subcutaneous; Pancreatic Elastase - administration & dosage; Pancreatic Elastase - pharmacology; Rabbits; Sodium Chloride - administration & dosage; Statistics, Nonparametric; Suture Techniques

Objective  To evaluate the effectiveness of contouring auricular cartilage in a rabbit model using biologically active enzymes injected subcutaneously.Methods  The first phase determined the most effective volume and concentration required to affect the cartilage. To accomplish this task, we used ex...