Tethered N‑Heterocyclic Carbene-Carboranyl Silver Complexes for Cancer Therapy

• Published in: Organometallics Vol. 38; no. 12; pp. 2530 - 2538
• Main Authors: Holmes, Jordan, Kearsey, Rachel J, Paske, Katie A, Singer, Frances N, Atallah, Suliman, Pask, Christopher M, Phillips, Roger M, Willans, Charlotte E
• Format: Journal Article
• Language: English
• Published: WASHINGTON American Chemical Society 24.06.2019; Amer Chemical Soc
• Subjects: Chemistry; Chemistry, Inorganic & Nuclear; Chemistry, Organic; Physical Sciences; Science & Technology; CAFFEINE; ANTICANCER ACTIVITY; DESIGN; CYTOTOXICITY

Silver complexes of tethered N-heterocyclic carbene-carboranyl ligands have been prepared and fully characterized. The first example of silver bonded directly to the cage of o-carborane has been identified in the solid state. The presence of a carboranyl N substituent on the N-heterocyclic carbene s...