Facially Amphiphilic Skeleton-Derived Antibacterial Cationic Dendrimers

• Published in: Biomacromolecules Vol. 24; no. 1; pp. 269 - 282
• Main Authors: Le, Mengqi, Huang, Wen, Ma, Zunwei, Shi, Zhifeng, Li, Qingtao, Lin, Caihong, Wang, Lin, Jia, Yong-Guang
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 09.01.2023
• Subjects: Anti-Bacterial Agents - pharmacology; Anti-Infective Agents - pharmacology; Dendrimers - pharmacology; Escherichia coli; Humans; Microbial Sensitivity Tests; Staphylococcus aureus

It is urgent to develop biocompatible and high-efficiency antimicrobial agents since microbial infections have always posed serious challenges to human health. Herein, through the marriage of facially amphiphilic skeletons and cationic dendrimers, high-density positively charged dendrimers D-CA6-N+...