PM2.5 Constituents and Oxidative DNA Damage in Humans

• Published in: Environmental science & technology Vol. 43; no. 13; pp. 4757 - 4762
• Main Authors: Wei, Yongjie, Han, In-Kyu, Shao, Min, Hu, Min, Zhang, Junfeng (Jim), Tang, Xiaoyan
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 01.07.2009
• Subjects: Adolescent; Adult; Air Pollutants - analysis; Air Pollution - analysis; Carbon - chemistry; Deoxyguanosine - analogs & derivatives; Deoxyguanosine - pharmacology; Deoxyguanosine - urine; DNA Damage; Humans; Metals - chemistry; Occupational Exposure; Oxidative Stress; Particulate Matter - toxicity; Respiratory System - drug effects; Universities; Vehicle Emissions - toxicity

Previous studies suggested that certain constituents of ambient PM2.5 can induce or increase oxidative stress in biological systems. The present study is designed to examine whether exposure to traffic generated particles increases the burden of oxidative stress in humans and to identify specific PM...