Flow limitation in liquid-filled lungs: effects of liquid properties

• Published in: Journal of biomechanical engineering Vol. 127; no. 4; p. 630
• Main Authors: Bull, Joseph L, Reickert, Craig A, Tredici, Stefano, Komori, Eisaku, Frank, Elizabeth L, Brant, David O, Grotberg, James B, Hirschl, Ronald B
• Format: Journal Article
• Language: English
• Published: United States 01.08.2005
• Subjects: Airway Resistance - physiology; Animals; Computer Simulation; Fluorocarbons - chemistry; Liquid Ventilation - methods; Lung - physiology; Lung Compliance - physiology; Models, Biological; Pressure; Rabbits; Respiratory Mechanics - physiology; Rheology - methods; Tidal Volume - physiology

Flow limitation in liquid-filled lungs is examined in intact rabbit experiments and a theoretical model. Flow limitation ("choked" flow) occurs when the expiratory flow reaches a maximum value and further increases in driving pressure do not increase the flow. In total liquid ventilation t...