USING GENETIC PROGRAMMING TO SELECT THE INFORMATIVE EEG-BASED FEATURES TO DISTINGUISH SCHIZOPHRENIC PATIENTS

• Published in: Neural Network World Vol. 22; no. 1; pp. 3 - 20
• Main Authors: Sabeti, Malihe, Boostani, Reza, Zoughi, Toktam
• Format: Journal Article
• Language: English
• Published: Prague Institute of Information and Computer Technology 01.01.2012; Institute of Computer Science
• Subjects: Electroencephalography; Genetic algorithms; Schizophrenia; Features selection; EEG; LDA; MLDA; GP; schizophrenic; Adaboost
• ISSN: 1210-0552; 2336-4335
• DOI: 10.14311/NNW.2012.22.001

There is growing interest to analyze electroencephalogram (EEG) signals with the objective of classifying schizophrenic patients from the control subjects. In this study, EEG signals of 15 schizophrenic patients and 19 age-matched control subjects are recorded using twenty surface electrodes. After the preprocessing phase, several features including autoregressive (AR) model coefficients, band power and fractal dimension were extracted from their recorded signals. Three classifiers including Linear Discriminant Analysis (LDA), Multi-LDA (MLDA) and Adaptive Boosting (Adaboost) were implemented to classify the EEG features of schizophrenic and normal subjects. Leave-one (participant)-out cross validation is performed in the training phase and finally in the test phase; the results of applying the LDA, MLDA and Adaboost respectively provided 78%, 81% and 82% classification accuracies between the two groups. For further improvement, Genetic Programming (GP) is employed to select more informative features and remove the redundant ones. After applying GP on the feature vectors, the results are remarkably improved so that the classification rate of the two groups with LDA, MLDA and Adaboost classifiers yielded 82%, 84% and 93% accuracies, respectively.