Lewis Acid-Catalyzed 1,4-Addition and Annulation of 4‑Hydroxy-coumarins with o‑Hydroxyphenyl Propargyl Amines: Entry to Regio-Selective Synthesis of Furano[3,2‑c]coumarins and Pyrano[3,2‑c]coumarins
A facile and regioselective Lewis acid-catalyzed cascade annulation of o-hydroxyphenyl propargyl amines with 4-hydroxycoumarin to afford furano[3,2-c]coumarin and pyrano[3,2-c]coumarin derivatives is reported. The reaction presumably proceeds by the conjugate addition of 4-hydroxycoumarin to the...
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Published in | Journal of organic chemistry Vol. 88; no. 7; pp. 4730 - 4742 |
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Main Authors | , |
Format | Journal Article |
Language | English |
Published |
WASHINGTON
American Chemical Society
07.04.2023
Amer Chemical Soc |
Subjects | |
Online Access | Get full text |
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