Circulating Proteins Associated with Anti-IL6 Receptor Therapeutic Resistance in the Sera of Patients with Severe COVID-19 - Michot, Jean-Marie; Dozio, Vito; Rohmer, Julien; Pommeret, Fanny; Roumier, Mathilde; Yu, Haochen; Sklodowki, Kamil; Danlos, François-Xavier; Ouali, Kaissa; Kishazi, Edina; Naigeon, Marie; Griscelli, Franck; et al. (Journal of proteome research, 2024)
Keywords: acute respiratory distress syndrome; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized - therapeutic use; Blood Proteins - analysis; Blood Proteins - metabolism; blood serum; Chromatography, Liquid - methods; complement; COVID-19 - blood; COVID-19 - mortality; COVID-19 - virology; COVID-19 Drug Treatment; COVID-19 infection; cytokines; distress; drugs; Female; Humans; Interleukin-6 - blood; intravenous injection; liquid chromatography; Male; Middle Aged; mortality; patients; physiological state; proteome; Proteome - analysis; proteomics; Proteomics - methods; Receptors, Interleukin-6 - antagonists & inhibitors; Receptors, Interleukin-6 - blood; SARS-CoV-2 - physiology; viruses; COVID-19; candidate proteins; proteomics; thrombospondin-1; anti-interleukin 6 receptor therapy; calprotectin