Synthesis and Quantitative Structure–Activity Relationship of Imidazotetrazine Prodrugs with Activity Independent of O6‑Methylguanine-DNA-methyltransferase, DNA Mismatch Repair, and p53 - Pletsas, Dimitrios; Garelnabi, Elrashied A. E; Li, Li; Phillips, Roger M; Wheelhouse, Richard T (Journal of medicinal chemistry, 2013)
Keywords: Base Pair Mismatch; Chemistry, Medicinal; DNA Repair; Life Sciences & Biomedicine; O-Methylguanine-DNA Methyltransferase - chemistry; Pharmacology & Pharmacy; Prodrugs - chemistry; Quantitative Structure-Activity Relationship; Science & Technology; Tumor Suppressor Protein p53 - metabolism; THERAPY-RELATED CANCER; ANTITUMOR DRUG TEMOZOLOMIDE; IN-VITRO; METHYLATING AGENTS; METHYLTRANSFERASE; MECHANISM; DISCOVERY SCREEN; DECOMPOSITION; ALKYLTRANSFERASE; MITOZOLOMIDE