Effect of a 24-Month Physical Activity Intervention vs Health Education on Cognitive Outcomes in Sedentary Older Adults: The LIFE Randomized Trial

• Published in: JAMA : the journal of the American Medical Association Vol. 314; no. 8; pp. 781 - 790
• Main Authors: Sink, Kaycee M, Espeland, Mark A, Castro, Cynthia M, Church, Timothy, Cohen, Ron, Dodson, John A, Guralnik, Jack, Hendrie, Hugh C, Jennings, Janine, Katula, Jeffery, Lopez, Oscar L, McDermott, Mary M, Pahor, Marco, Reid, Kieran F, Rushing, Julia, Verghese, Joe, Rapp, Stephen, Williamson, Jeff D
• Format: Journal Article
• Language: English
• Published: United States American Medical Association 25.08.2015
• Subjects: Age Factors; Aged; Aged, 80 and over; Cognition & reasoning; Cognitive Dysfunction - epidemiology; Cognitive Dysfunction - prevention & control; Dementia - epidemiology; Dementia - prevention & control; Executive Function; Exercise Therapy - methods; Female; Health Education; Health Promotion; Humans; Male; Muscle Stretching Exercises; Older people; Physical fitness; Resistance Training; Sedentary Behavior; Treatment Outcome; Upper Extremity; Walking

IMPORTANCE: Epidemiological evidence suggests that physical activity benefits cognition, but results from randomized trials are limited and mixed. OBJECTIVE: To determine whether a 24-month physical activity program results in better cognitive function, lower risk of mild cognitive impairment (MCI)...