Microfluidics for Development of Lipid Nanoparticles: Paving the Way for Nucleic Acids to the Clinic

• Published in: ACS applied bio materials Vol. 6; no. 9; pp. 3566 - 3576
• Main Authors: Ali, Moustafa S., Hooshmand, Nasrin, El-Sayed, Mostafa, Labouta, Hagar I.
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 18.09.2023
• Subjects: nanomedicine; nucleic acid therapies; microfluidics; mRNA, lipid nanoparticles
• ISSN: 2576-6422; 2576-6422
• DOI: 10.1021/acsabm.1c00732

Nucleic acid therapeutics hold an unprecedented promise toward treating many challenging diseases; however, their use is hampered by delivery issues. Microfluidics, dealing with fluids in the microscale dimensions, have provided a robust means to screening raw materials for development of nano deliv...