Platelet Membrane-Coated HGF-PLGA Nanoparticles Promote Therapeutic Angiogenesis and Tissue Perfusion Recovery in Ischemic Hindlimbs - Wang, Peng; Di, Xiao; Li, Fengshi; Rong, Zhihua; Lian, Wenzhuo; Li, Zongshu; Chen, Tianqi; Wang, Wenjing; Zhong, Qing; Sun, Guoqiang; Ni, Leng; Liu, ChangWei (ACS applied bio materials, 2025)
Keywords: Angiogenesis; Animals; Biocompatible Materials - chemistry; Biocompatible Materials - pharmacology; Blood Platelets - chemistry; Cell Movement - drug effects; Cell Proliferation - drug effects; Hepatocyte Growth Factor - chemistry; Hepatocyte Growth Factor - pharmacology; Hindlimb - blood supply; Hindlimb - drug effects; Humans; Ischemia - drug therapy; Male; Materials Testing; Nanoparticles - chemistry; Neovascularization, Physiologic - drug effects; Particle Size; Polylactic Acid-Polyglycolic Acid Copolymer - chemistry; Polylactic Acid-Polyglycolic Acid Copolymer - pharmacology; Rats; Rats, Sprague-Dawley; Surface Properties; therapeutic angiogenesis; peripheral artery disease; drug delivery; chronic limb-threatening ischemia; hepatocyte growth factor