NIR Photocontrolled Fluorescent Nanosensor under a Six-Branched DNA Nanowheel-Induced Nucleic Acid Confinement Effect for High-Performance Bioimaging

• Published in: ACS applied materials & interfaces Vol. 15; no. 8; pp. 10529 - 10540
• Main Authors: Liu, Jun-Xian, Xin, Meng-Kun, Sun, Xiaoming, Liu, Da, Li, Cheng-Yu
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 01.03.2023
• Subjects: Animals; Biological and Medical Applications of Materials and Interfaces; Biosensing Techniques - methods; Coloring Agents; DNA; Mice; MicroRNAs - genetics; Nanoparticles - chemistry; Nucleic Acids - chemistry; DNA nanotechnology; microRNA; upconversion luminescence; biosensor; bioimaging

Although DNA nanotechnology is a promising option for fluorescent biosensors to perform bioimaging, the uncontrollable target identification during biological delivery and the spatially free molecular collision of nucleic acids may cause unsatisfactory imaging precision and sensitivity, respectively...