Heterogeneous Asymmetric Hydrogenation of Prochiral Alkenoic Acid: Origin of Rate and Enantioselectivity Enhancement by Amine Addition

• Published in: ACS catalysis Vol. 2; no. 3; pp. 464 - 467
• Main Authors: Meemken, Fabian, Maeda, Nobutaka, Hungerbühler, Konrad, Baiker, Alfons
• Format: Journal Article
• Language: English
• Published: American Chemical Society 02.03.2012
• Subjects: chiral modifier; heterogeneous catalysis; in situ IR spectroscopy; modulation excitation spectroscopy; asymmetric hydrogenation

The origin of rate and enantioselectivity enhancement by achiral amine addition in the asymmetric hydrogenation of alkenoic acid on chirally modified Pd has been a long-debated subject. We show by means of in situ attenuated total reflection infrared spectroscopy combined with modulation excitation...