Isoprenylated Flavonoids from the Stem Bark of Erythrina abyssinica

• Published in: Journal of natural products (Washington, D.C.) Vol. 70; no. 6; pp. 1039 - 1042
• Main Authors: Cui, Long, Ndinteh, Derek Tantoh, Na, MinKyun, Thuong, Phuong Thien, Silike-Muruumu, John, Njamen, Dieudonné, Mbafor, Joseph Tanyi, Fomum, Zacharias Tanee, Ahn, Jong Seog, Oh, Won Keun
• Format: Journal Article
• Language: English
• Published: Washington, DC American Chemical Society 01.06.2007; Glendale, AZ American Society of Pharmacognosy
• Subjects: 2S-5,7-dihydroxy-2'',2''-dimethylpyrano[5'',6'',3',4']flavanone; abyssinoflavanones; Biological and medical sciences; chemical structure; Erythrina; Erythrina - chemistry; Erythrina abyssinica; Fabaceae; flavanones; flavonoids; Flavonoids - chemistry; Flavonoids - isolation & purification; Flavonoids - pharmacology; General pharmacology; human health; Humans; Inhibitory Concentration 50; insulin; Medical sciences; medicinal properties; Molecular Structure; noninsulin-dependent diabetes mellitus; Pharmacognosy. Homeopathy. Health food; Pharmacology. Drug treatments; physicochemical properties; Plant Bark - chemistry; Plant Stems - chemistry; Plants, Medicinal - chemistry; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases - antagonists & inhibitors; Protein Tyrosine Phosphatases - genetics; protein-tyrosine-phosphatase; signal transduction; spectral analysis; Uganda; Uganda; Enzyme; Pharmacognosy; Bark; Phosphoric monoester hydrolases; Enzyme inhibitor; Esterases; Isoprenoid; Flavonoid; In vitro; Biological activity; Stem; Flavanone derivatives; Medicinal plant; Leguminosae; Dicotyledones; Angiospermae; Plant origin; Hydrolases; Isolation; Spermatophyta; Structural analysis; Protein-tyrosine-phosphatase

Three new prenylated flavanones, abyssinoflavanones V, VI, and VII (1−3), together with eight known flavanones (4−11) and two chalcones (12−13), were isolated from the stem bark of Erythrina abyssinica. Their structures were elucidated on the basis of spectroscopic and physicochemical analyses. All...