Osmotic Pressure Induced Morphological Transformation of Membranized Coacervates

• Published in: Journal of the American Chemical Society Vol. 147; no. 20; pp. 17022 - 17033
• Main Authors: Qiao, Xin, Wang, Xiaoliang, Chen, Haixu, Huang, Yan, Li, Shangsong, Li, Luxuan, Huang, Xin
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 21.05.2025
• Subjects: actin; Artificial Cells - chemistry; cholesterol; Cholesterol - chemistry; deformation; dissociation; Endocytosis; enzymatic reactions; Osmotic Pressure; phospholipids; Phospholipids - chemistry; polymerization; Staphylococcus aureus; Staphylococcus aureus - metabolism; vacuoles

The stimulus-response behavior of protocells under environmental osmotic pressure changes has long been a subject of scientific inquiry. Herein, we demonstrate a way to membranized coacervate microdroplets based on cholesterol anchoring of phospholipids, which provides enhanced stability, enabling m...