EnzymePredictor: A Tool for Predicting and Visualizing Enzymatic Cleavages of Digested Proteins

• Published in: Journal of proteome research Vol. 11; no. 12; pp. 6056 - 6065
• Main Authors: Vijayakumar, Vaishnavi, Guerrero, Andrés N, Davey, Norman, Lebrilla, Carlito B, Shields, Denis C, Khaldi, Nora
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 07.12.2012
• Subjects: Amino Acid Sequence; Catalytic Domain; Chymotrypsin - chemistry; Databases, Protein; Enzyme Assays - methods; Enzymes - chemistry; Humans; Mass Spectrometry; Milk, Human - chemistry; Milk, Human - enzymology; Molecular Sequence Data; Odds Ratio; Peptide Mapping - methods; Peptides - chemistry; Protein Hydrolysates - chemistry; Proteolysis; Software; Substrate Specificity; Time Factors; Trypsin - chemistry; protein digestion; hydrolysate; enzyme cleavage; peptides; fermentation; mass spectrometry; mass spectrometry visualization

Mass spectrometric analysis of peptides contained in enzymatically digested hydrolysates of proteins is increasingly being used to characterize potentially bioactive or otherwise interesting hydrolysates. However, when preparations containing mixtures of enzymes are used, from either biological or e...