Higher-Order Assembly of Collagen Peptides into Nano- and Microscale Materials

• Published in: Biochemistry (Easton) Vol. 49; no. 21; pp. 4411 - 4419
• Main Authors: Przybyla, David E, Chmielewski, Jean
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 01.06.2010
• Subjects: Biocompatible Materials - analysis; Biocompatible Materials - chemistry; Biocompatible Materials - metabolism; Collagen - analysis; Collagen - chemistry; Drug Delivery Systems - adverse effects; Extracellular Matrix - chemistry; Extracellular Matrix - metabolism; Manufactured Materials - analysis; Peptides - analysis; Peptides - chemistry; Peptides - metabolism; Tissue Engineering - methods

The triple-helical structure of collagen peptides has recently been harnessed as a subunit in the higher-order assembly of unique biomaterials. Specific assembly signals have been designed within collagen peptides, including hydrophobic groups, electrostatic interactions, and metal−ligand binding, t...