syn-Selective Construction of Fused Heterocycles by Catalytic Reductive Tandem Functionalization of N‑Heteroarenes

• Published in: ACS catalysis Vol. 11; no. 15; pp. 9271 - 9278
• Main Authors: Yang, Jian, Zhao, He, Tan, Zhenda, Cao, Liang, Jiang, Huanfeng, Ci, Chenggang, Dixneuf, Pierre H, Zhang, Min
• Format: Journal Article
• Language: English
• Published: American Chemical Society 06.08.2021
• Subjects: Chemical Sciences; diastereoselectivity; ruthenium catalysis; tandem functionalization; N-heteroarenes; reductive dearomatization

To date, numerous methods have been successfully developed to functionalize N-heteroaryl C–H bonds. In contrast, dearomative tandem functionalization of N-heteroarenes is still a subject to be explored. Reported herein is an example on reductive dearomatization-induced tandem functionalization of N-...