Total Synthesis of (±)-Biphyscion

• Published in: Organic letters Vol. 1; no. 4; pp. 671 - 672
• Main Authors: Hauser, Frank M, Gauuan, Polivina Jolicia F
• Format: Journal Article
• Language: English
• Published: WASHINGTON American Chemical Society 26.08.1999; Amer Chemical Soc
• Subjects: Anthraquinones - chemical synthesis; Chemistry; Chemistry, Organic; Magnetic Resonance Spectroscopy; Physical Sciences; Science & Technology

A regiospecific total synthesis of (±)-biphyscion (1) is described. A novel aspect of the plan was construction of the bianthraquinone ring system from a biphenyl intermediate through the use of a one-pot, double isobenzofuranone condensation.