Determination of Absolute Configurations of Amines and Amino Acids Using Nonchiral Derivatizing Agents (NCDA) and Deuterium NMR
Enantiomeric analysis and empirical determination of the absolute configuration of amines and amino acids can be easily performed using acetyl-d 3 chloride as a nonchiral derivatizing agent (deuterium probe) and deuterium NMR in a chiral solvent (Courtieu's method). In the case of amino acids,...
Saved in:
| Published in | Organic letters Vol. 2; no. 16; pp. 2431 - 2434 |
|---|---|
| Main Authors | , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
WASHINGTON
American Chemical Society
10.08.2000
Amer Chemical Soc |
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Abstract | Enantiomeric analysis and empirical determination of the absolute configuration of amines and amino acids can be easily performed using acetyl-d 3 chloride as a nonchiral derivatizing agent (deuterium probe) and deuterium NMR in a chiral solvent (Courtieu's method). In the case of amino acids, derivatization to amido esters, performed with methanol-d 4 and acetyl-d 3 chloride, gives a double opportunity for enantiomeric analysis. |
|---|---|
| AbstractList | Enantiomeric analysis and empirical determination of the absolute configuration of amines and amino acids can be easily performed using acetyl-d(3) chloride as a nonchiral derivatizing agent (deuterium probe) and deuterium NMR in a chiral solvent (Courtieu's method). In the case of amino acids, derivatization to amido esters, performed with methanol-d(4) and acetyl-d(3) chloride, gives a double opportunity for enantiomeric analysis. [GRAPHICS] Enantiomeric analysis end empirical determination of the absolute configuration of amines and amino acids can be easily performed using acetyl-d(3) chloride as a nonchiral derivatizing agent (deuterium probe) and deuterium NMR in a chiral solvent (Courtieu's method), In the case of amino acids, derivatization to amido esters, performed with methanol-d(4) and acetyl-d(3) chloride, gives a double opportunity for enantiomeric analysis. |
| Author | Bertrand, Magali Canet, Isabelle Chalard, Pierre Théry, Vincent Remuson, Roland Jeminet, Georges |
| Author_xml | – sequence: 1 givenname: Pierre surname: Chalard fullname: Chalard, Pierre – sequence: 2 givenname: Magali surname: Bertrand fullname: Bertrand, Magali – sequence: 3 givenname: Isabelle surname: Canet fullname: Canet, Isabelle – sequence: 4 givenname: Vincent surname: Théry fullname: Théry, Vincent – sequence: 5 givenname: Roland surname: Remuson fullname: Remuson, Roland – sequence: 6 givenname: Georges surname: Jeminet fullname: Jeminet, Georges |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/10956514$$D View this record in MEDLINE/PubMed |
| BookMark | eNqNkU1L7DAUhoMofi_8A5LNvSgymqSTfixLxy_QEUTXJU1O50baRJP2im7862ZaGVy4MJscznnel8N7dtC6sQYQOqDklBJGz2xDSEzieLGGtiln0SQhnK2v6phsoR3vnwihoZNtoi1KMh5zOt1GHzPowLXaiE5bg22N88rbpu8AF9bUetG7YeKHUeDAY2HUUFqcS608fvTaLPDcGvlPO9HgGTj9P6jel-18Aabz-GhezPLjQTqD4O503-L57f0e2qhF42H_699FjxfnD8XV5Obu8rrIbyYiorSbJFNVRRnjalonSZVGIspolGSSqYrGkKWgakkyKTjl1VTwBIQMTSEUKFLFNYt20d_R99nZlx58V7baS2gaYcD2vkwYIyylPIDHIyid9d5BXT473Qr3VlJSLtMuV2kH9vDLtK9aUN_IMd4AnIzAK1S29lKDkbDCSHhpGodbkeVpAp3-ni50NxymsL3pgvTPKBXSl0-2dyaE-cPGnzUmqYE |
| CitedBy_id | crossref_primary_10_1002_chir_10158 crossref_primary_10_1002_mrc_2374 crossref_primary_10_1002_chir_10190 crossref_primary_10_1002_mrc_1716 crossref_primary_10_1021_ol020038b crossref_primary_10_1002_chem_200390199 crossref_primary_10_1016_j_tetasy_2005_05_012 crossref_primary_10_1021_acs_orglett_7b01748 crossref_primary_10_1021_ja310620c crossref_primary_10_1515_boca_2015_0003 |
| Cites_doi | 10.1021/ja00129a015 10.1006/bioo.1993.1029 10.1021/ja00100a033 10.1016/S0957-4166(96)00533-2 10.1021/j100785a001 10.1021/jo961141f 10.1021/jo9604191 10.1021/ja00741a013 10.1021/jo00952a006 10.1016/S0957-4166(98)00468-6 10.1021/ja00084a070 10.1021/jo00232a015 |
| ContentType | Journal Article |
| Copyright | Copyright © 2000 American Chemical Society |
| Copyright_xml | – notice: Copyright © 2000 American Chemical Society |
| DBID | 1KM BLEPL DTL FKBAJ CGR CUY CVF ECM EIF NPM AAYXX CITATION 7X8 |
| DOI | 10.1021/ol006066g |
| DatabaseName | Index Chemicus Web of Science Core Collection Science Citation Index Expanded Web of Science - Science Citation Index Expanded - 2000 Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed CrossRef MEDLINE - Academic |
| DatabaseTitle | Web of Science MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) CrossRef MEDLINE - Academic |
| DatabaseTitleList | MEDLINE Web of Science |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: 1KM name: Index Chemicus url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/woscc/search-with-editions?editions=WOS.IC sourceTypes: Enrichment Source Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Chemistry |
| EISSN | 1523-7052 |
| EndPage | 2434 |
| ExternalDocumentID | 10_1021_ol006066g 10956514 000088605200011 d119715328 |
| Genre | Journal Article |
| GroupedDBID | - .K2 123 53G 55A 5VS 7~N AABXI ABFLS ABMVS ABPTK ABUCX ACGFS ACS AEESW AENEX AETEA AFEFF ALMA_UNASSIGNED_HOLDINGS AQSVZ BAANH CS3 DU5 DZ EBS ED ED~ EJD F5P G8K GNL IH9 IHE JG JG~ K2 LG6 P2P RNS ROL TN5 UI2 UNC VF5 VG9 W1F X YNT ZY4 --- -DZ -~X 1KM AAHBH ABJNI ABQRX ADHLV AHGAQ BLEPL CUPRZ DTL GGK GROUPED_WOS_SCIENCE_CITATION_INDEX_EXPANDED CGR CUY CVF ECM EIF NPM AAYXX CITATION 7X8 |
| ID | FETCH-LOGICAL-a311t-74db3925d4f77b83a391379c2db16e98edfc09ca515b4a57eac98eaaded0b6f23 |
| IEDL.DBID | ACS |
| ISICitedReferencesCount | 14 |
| ISICitedReferencesURI | https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestApp=WOS&DestLinkType=CitingArticles&UT=000088605200011 |
| ISSN | 1523-7060 |
| IngestDate | Thu Oct 24 23:08:20 EDT 2024 Thu Sep 26 19:02:28 EDT 2024 Tue Oct 22 02:25:21 EDT 2024 Wed Sep 18 05:13:37 EDT 2024 Fri Nov 08 19:45:18 EST 2024 Thu Aug 27 13:42:19 EDT 2020 |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 16 |
| Keywords | H-1-NMR REAGENT LYOTROPIC LIQUID-CRYSTAL ENANTIOMERIC ANALYSIS ASSIGNMENT CHIRAL PRIMARY AMINES MTPA AMIDES |
| Language | English |
| LinkModel | DirectLink |
| LogoURL | https://exlibris-pub.s3.amazonaws.com/fromwos-v2.jpg |
| MergedId | FETCHMERGED-LOGICAL-a311t-74db3925d4f77b83a391379c2db16e98edfc09ca515b4a57eac98eaaded0b6f23 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| PMID | 10956514 |
| PQID | 72202815 |
| PQPubID | 23479 |
| PageCount | 4 |
| ParticipantIDs | webofscience_primary_000088605200011 proquest_miscellaneous_72202815 acs_journals_10_1021_ol006066g pubmed_primary_10956514 crossref_primary_10_1021_ol006066g webofscience_primary_000088605200011CitationCount |
| ProviderPackageCode | JG~ 55A AABXI GNL VF5 7~N VG9 W1F ACS AEESW AFEFF .K2 ABMVS ABUCX IH9 BAANH AQSVZ ED~ UI2 |
| PublicationCentury | 2000 |
| PublicationDate | 2000-08-10 |
| PublicationDateYYYYMMDD | 2000-08-10 |
| PublicationDate_xml | – month: 08 year: 2000 text: 2000-08-10 day: 10 |
| PublicationDecade | 2000 |
| PublicationPlace | WASHINGTON |
| PublicationPlace_xml | – name: WASHINGTON – name: United States |
| PublicationTitle | Organic letters |
| PublicationTitleAbbrev | ORG LETT |
| PublicationTitleAlternate | Org. Lett |
| PublicationYear | 2000 |
| Publisher | American Chemical Society Amer Chemical Soc |
| Publisher_xml | – name: American Chemical Society – name: Amer Chemical Soc |
| References | TROST, BM (WOS:A1994PA24400035) 1994; 59 ELIEL EL (WOS:000088605200011.11) 1994 SULLIVAN, GR (WOS:A1973P889200006) 1973; 38 HEATHCOCK, CH (WOS:A1992HR52200007) 1992; 57 Hoye, TR (WOS:A1996VV60900026) 1996; 61 CANET, I (WOS:A1995RE57500015) 1995; 117 Lopez, B (WOS:000083280100030) 1999; 121 URAY G (WOS:000088605200011.22) 1996; 1 Chinchilla, R (WOS:A1996VN44100016) 1996; 61 BESSE, P (WOS:A1993LY63800009) 1993; 21 Chalard, P (WOS:000077920000011) 1998; 9 Canet, JL (WOS:A1996VY22000057) 1996; 61 BONDI, A (WOS:A19646650B00003) 1964; 68 BORCH, RF (WOS:A1971J573500013) 1971; 93 Seco, JM (WOS:A1997YD81100015) 1997; 62 CANET, I (WOS:A1994NB16900070) 1994; 116 Meddour, A (WOS:A1997WJ13200023) 1997; 8 Seco, JM (WOS:000081136200018) 1999; 64 BERNASCONI, S (WOS:A1977DG40400021) 1977; 107 Chalard, P (WOS:000078624500014) 1999; 40 MEDDOUR, A (WOS:A1994PN45200033) 1994; 116 ROUSH, WR (WOS:A1987K882700014) 1987; 52 Roush W. R. (ol006066gb00008/ol006066gb00008_1) 1987; 52 Meddour A. (ol006066gb00004/ol006066gb00004_1) 1994; 116 ol006066gb00010/ol006066gb00010_1 Canet J. L. (ol006066gb00005/ol006066gb00005_2) 1996; 61 Bernasconi S. (ol006066gb00009/ol006066gb00009_1) 1977; 107 Hoye T. R. (ol006066gb00002/ol006066gb00002_4) 1996; 61 Borch R. F. (ol006066gb00006/ol006066gb00006_1) 1971; 93 Sullivan G. R. (ol006066gb00003/ol006066gb00003_1) 1973; 38 Bondi A. (ol006066gb00013/ol006066gb00013_1) 1964; 68 Canet I. (ol006066gb00005/ol006066gb00005_1) 1994; 116 Chinchilla R. (ol006066gb00002/ol006066gb00002_3) 1996; 61 Meddour A. (ol006066gb00005/ol006066gb00005_3) 1997; 8 Besse P. (ol006066gb00007/ol006066gb00007_1) 1993; 21 Seco J. M. (ol006066gb00003/ol006066gb00003_3) 1997; 62 Canet I. (ol006066gb00004/ol006066gb00004_2) 1995; 117 Lopez B. (ol006066gb00002/ol006066gb00002_1) 1999; 121 Trost B. M. (ol006066gb00003/ol006066gb00003_2) 1994; 59 Seco J. M. (ol006066gb00002/ol006066gb00002_2) 1999; 64 For (ol006066gb00001/ol006066gb00001_1) 1996; 1 |
| References_xml | – volume: 116 start-page: 2155 year: 1994 ident: WOS:A1994NB16900070 article-title: NEW, AND ACCURATE METHOD TO DETERMINE THE ENANTIOMERIC PURITY OF AMINO-ACIDS BASED ON DEUTERIUM NMR IN A CHOLESTERIC LYOTROPIC LIQUID-CRYSTAL publication-title: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY contributor: fullname: CANET, I – volume: 93 start-page: 2897 year: 1971 ident: WOS:A1971J573500013 article-title: CYANOHYDRIDOBORATE ANION AS A SELECTIVE REDUCING AGENT publication-title: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY contributor: fullname: BORCH, RF – year: 1994 ident: WOS:000088605200011.11 publication-title: STEREOCHEMISTRY ORGA contributor: fullname: ELIEL EL – volume: 38 start-page: 2143 year: 1973 ident: WOS:A1973P889200006 article-title: CORRELATION OF CONFIGURATION AND F-19 CHEMICAL-SHIFTS OF ALPHA-METHOXY-ALPHA-TRIFLUOROMETHYLPHENYLACETATE DERIVATIVES publication-title: JOURNAL OF ORGANIC CHEMISTRY contributor: fullname: SULLIVAN, GR – volume: 107 start-page: 95 year: 1977 ident: WOS:A1977DG40400021 article-title: SYNTHESIS OF (2S,4S) AND (2R,4S)-2-AMINO-4-METHYLEXANOIC ACID (HOMOLEUCINE) publication-title: GAZZETTA CHIMICA ITALIANA contributor: fullname: BERNASCONI, S – volume: 62 start-page: 7569 year: 1997 ident: WOS:A1997YD81100015 article-title: Choosing the right reagent for the determination of the absolute configuration of amines by NMR: MTPA or MPA? publication-title: JOURNAL OF ORGANIC CHEMISTRY contributor: fullname: Seco, JM – volume: 59 start-page: 4202 year: 1994 ident: WOS:A1994PA24400035 article-title: ON THE USE OF O-METHYLMANDELIC ACID FOR THE ESTABLISHMENT OF ABSOLUTE-CONFIGURATION OF ALPHA-CHIRAL PRIMARY AMINES publication-title: JOURNAL OF ORGANIC CHEMISTRY contributor: fullname: TROST, BM – volume: 61 start-page: 7285 year: 1996 ident: WOS:A1996VN44100016 article-title: Determination of the absolute configuration of amines and alpha-amino acids by H-1 NMR of (R)-O-aryllactic acid amides publication-title: JOURNAL OF ORGANIC CHEMISTRY contributor: fullname: Chinchilla, R – volume: 68 start-page: 441 year: 1964 ident: WOS:A19646650B00003 article-title: VAN DER WAALS VOLUMES + RADII publication-title: JOURNAL OF PHYSICAL CHEMISTRY contributor: fullname: BONDI, A – volume: 21 start-page: 342 year: 1993 ident: WOS:A1993LY63800009 article-title: BAKERS-YEAST REDUCTION OF ALPHA-DIKETONES - INVESTIGATION AND CONTROL OF THE ENZYMATIC PATHWAY publication-title: BIOORGANIC CHEMISTRY contributor: fullname: BESSE, P – volume: 64 start-page: 4669 year: 1999 ident: WOS:000081136200018 article-title: Boc-phenylglycine: The reagent of choice for the assignment of. The absolute configuration of alpha-chiral primary amines by H-1 NMR spectroscopy publication-title: JOURNAL OF ORGANIC CHEMISTRY contributor: fullname: Seco, JM – volume: 1 start-page: 253 year: 1996 ident: WOS:000088605200011.22 publication-title: HOUBENWEYL METHODS O contributor: fullname: URAY G – volume: 61 start-page: 8489 year: 1996 ident: WOS:A1996VV60900026 article-title: Applications of MTPA (Mosher) amides of secondary amines: Assignment of absolute configuration in chiral cyclic amines publication-title: JOURNAL OF ORGANIC CHEMISTRY contributor: fullname: Hoye, TR – volume: 57 start-page: 2531 year: 1992 ident: WOS:A1992HR52200007 article-title: DAPHNIPHYLLUM ALKALOIDS .10. CLASSICAL TOTAL SYNTHESIS OF METHYL HOMODAPHNIPHYLLATE publication-title: JOURNAL OF ORGANIC CHEMISTRY contributor: fullname: HEATHCOCK, CH – volume: 116 start-page: 9652 year: 1994 ident: WOS:A1994PN45200033 article-title: OBSERVATION OF ENANTIOMERS, CHIRAL BY VIRTUE OF ISOTOPIC-SUBSTITUTION, THROUGH DEUTERIUM NMR IN A POLYPEPTIDE LIQUID-CRYSTAL publication-title: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY contributor: fullname: MEDDOUR, A – volume: 8 start-page: 485 year: 1997 ident: WOS:A1997WJ13200023 article-title: An achiral deuterated derivatizing agent for enantiomeric analysis through NMR in a liquid crystalline solvent publication-title: TETRAHEDRON-ASYMMETRY contributor: fullname: Meddour, A – volume: 61 start-page: 9035 year: 1996 ident: WOS:A1996VY22000057 article-title: Acetyl-d(3) chloride: A convenient nonchiral derivatizing agent (NCDA) for a facile enantiomeric excess determination of amines through deuterium NMR publication-title: JOURNAL OF ORGANIC CHEMISTRY contributor: fullname: Canet, JL – volume: 9 start-page: 4361 year: 1998 ident: WOS:000077920000011 article-title: Asymmetric synthesis of quinolizidine alkaloids (-)-lasubine I, (-)-lasubine II and (+)-subcosine II publication-title: TETRAHEDRON-ASYMMETRY contributor: fullname: Chalard, P – volume: 117 start-page: 6520 year: 1995 ident: WOS:A1995RE57500015 article-title: ENANTIOMERIC ANALYSIS IN A POLYPEPTIDE LYOTROPIC LIQUID-CRYSTAL BY DEUTERIUM NMR publication-title: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY contributor: fullname: CANET, I – volume: 40 start-page: 1661 year: 1999 ident: WOS:000078624500014 article-title: Enantioselective synthesis of (-)-indolizidine 167B publication-title: TETRAHEDRON LETTERS contributor: fullname: Chalard, P – volume: 52 start-page: 5127 year: 1987 ident: WOS:A1987K882700014 article-title: TOTAL SYNTHESIS OF CARBOHYDRATES .5. STEREOCHEMISTRY OF THE EPOXIDATIONS OF ACYCLIC ALLYLIC AMIDES - APPLICATIONS TOWARD THE SYNTHESIS OF 2,3,6-TRIDEOXY-3-AMINOHEXOSES publication-title: JOURNAL OF ORGANIC CHEMISTRY contributor: fullname: ROUSH, WR – volume: 121 start-page: 9724 year: 1999 ident: WOS:000083280100030 article-title: Complexation with barium(II) allows the inference of the absolute configuration of primary amines by NMR publication-title: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY contributor: fullname: Lopez, B – volume: 121 start-page: 9725 year: 1999 ident: ol006066gb00002/ol006066gb00002_1 publication-title: J. Am. Chem. Soc. contributor: fullname: Lopez B. – volume: 62 start-page: 7574 year: 1997 ident: ol006066gb00003/ol006066gb00003_3 publication-title: J. Org. Chem. contributor: fullname: Seco J. M. – volume: 117 start-page: 6526 year: 1995 ident: ol006066gb00004/ol006066gb00004_2 publication-title: J. Am. Chem. Soc. doi: 10.1021/ja00129a015 contributor: fullname: Canet I. – volume: 107 start-page: 99 year: 1977 ident: ol006066gb00009/ol006066gb00009_1 publication-title: Gazz. Chim. Ital. contributor: fullname: Bernasconi S. – volume: 21 start-page: 353 year: 1993 ident: ol006066gb00007/ol006066gb00007_1 publication-title: Bioorg. Chem. doi: 10.1006/bioo.1993.1029 contributor: fullname: Besse P. – volume: 61 start-page: 8495 year: 1996 ident: ol006066gb00002/ol006066gb00002_4 publication-title: J. Org. Chem. contributor: fullname: Hoye T. R. – volume: 116 start-page: 9656 year: 1994 ident: ol006066gb00004/ol006066gb00004_1 publication-title: J. Am. Chem. Soc. doi: 10.1021/ja00100a033 contributor: fullname: Meddour A. – volume: 8 start-page: 494 year: 1997 ident: ol006066gb00005/ol006066gb00005_3 publication-title: Asymmetry doi: 10.1016/S0957-4166(96)00533-2 contributor: fullname: Meddour A. – volume: 68 start-page: 451 year: 1964 ident: ol006066gb00013/ol006066gb00013_1 publication-title: J. Phys. Chem. doi: 10.1021/j100785a001 contributor: fullname: Bondi A. – volume: 61 start-page: 9037 year: 1996 ident: ol006066gb00005/ol006066gb00005_2 publication-title: J. Org. Chem. doi: 10.1021/jo961141f contributor: fullname: Canet J. L. – volume: 1 start-page: 253 year: 1996 ident: ol006066gb00001/ol006066gb00001_1 publication-title: Stuttgart contributor: fullname: For – volume: 61 start-page: 7290 year: 1996 ident: ol006066gb00002/ol006066gb00002_3 publication-title: J. Org. Chem. doi: 10.1021/jo9604191 contributor: fullname: Chinchilla R. – volume: 93 start-page: 2897 year: 1971 ident: ol006066gb00006/ol006066gb00006_1 publication-title: J. Am. Chem. Soc. doi: 10.1021/ja00741a013 contributor: fullname: Borch R. F. – volume: 38 start-page: 2147 year: 1973 ident: ol006066gb00003/ol006066gb00003_1 publication-title: J. Org. Chem. doi: 10.1021/jo00952a006 contributor: fullname: Sullivan G. R. – volume: 59 start-page: 4205 year: 1994 ident: ol006066gb00003/ol006066gb00003_2 publication-title: J. Org. Chem. contributor: fullname: Trost B. M. – ident: ol006066gb00010/ol006066gb00010_1 doi: 10.1016/S0957-4166(98)00468-6 – volume: 64 start-page: 4675 year: 1999 ident: ol006066gb00002/ol006066gb00002_2 publication-title: J. Org. Chem. contributor: fullname: Seco J. M. – volume: 116 start-page: 2156 year: 1994 ident: ol006066gb00005/ol006066gb00005_1 publication-title: J. Am. Chem. Soc. doi: 10.1021/ja00084a070 contributor: fullname: Canet I. – volume: 52 start-page: 5136 year: 1987 ident: ol006066gb00008/ol006066gb00008_1 publication-title: J. Org. Chem. doi: 10.1021/jo00232a015 contributor: fullname: Roush W. R. |
| SSID | ssj0011529 |
| Score | 1.7385863 |
| Snippet | Enantiomeric analysis and empirical determination of the absolute configuration of amines and amino acids can be easily performed using acetyl-d 3 chloride as... [GRAPHICS] Enantiomeric analysis end empirical determination of the absolute configuration of amines and amino acids can be easily performed using acetyl-d(3)... Enantiomeric analysis and empirical determination of the absolute configuration of amines and amino acids can be easily performed using acetyl-d(3) chloride as... |
| Source | Web of Science |
| SourceID | proquest crossref pubmed webofscience acs |
| SourceType | Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 2431 |
| SubjectTerms | Amines - chemistry Amino Acids - chemistry Chemistry Chemistry, Organic Chymotrypsin Deuterium Indicators and Reagents Magnetic Resonance Spectroscopy - methods Molecular Conformation Physical Sciences Science & Technology Stereoisomerism |
| Title | Determination of Absolute Configurations of Amines and Amino Acids Using Nonchiral Derivatizing Agents (NCDA) and Deuterium NMR |
| URI | http://dx.doi.org/10.1021/ol006066g http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestApp=WOS&DestLinkType=FullRecord&UT=000088605200011 https://www.ncbi.nlm.nih.gov/pubmed/10956514 https://search.proquest.com/docview/72202815 |
| Volume | 2 |
| WOS | 000088605200011 |
| WOSCitedRecordID | wos000088605200011 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV1LT9wwEB5RemgvpS2v0EKtwgEOoTgvx8coKUKV2ENbJG6RX9mugKQiyYULf52xs1ltBaW9RX4ksmfs-ZyZ-QxwYAw3nInETyrO_Shm1E-pkj5iYzS_Jq5CR5J0PknOLqJvl_HlCuz_xYMf0C_NteUMSZLpC3gZMFwUFv_kPxauAjRA3JGiBqFvqWBG-qDlrtb0qPZP0_MITz5pepyZOV2DYkzWGaJLro77Th6ru8fcjc-N4C28mcNMkg168Q5WTP0eXuXj7W7rcF-McTBWMqSpSCadGhpikwBn035QjdZV3djgeCJq7R4bkqmZbokLNyCTpla_Zrf4tQK12f7hvbPFmc3ZasnhJC-yI9e1MPb6iFl_Qybn3zfg4vTrz_zMn1_G4IuQ0s5nkZaIpWIdVYzJNBQhpyHjKtCSJoanRlfqhCuB-EhGIma4oWOhENroE5lUQbgJq3VTm20gOrKHSh5XiD4jSWPBmVI8qoTRKW4gyoM9lFY5X0xt6fzkAS0X8-jB51GQ5e-BlOOpRp9GEZc4t9YPImrT9G3JggBRFY092Bokv_QSPC4ihPTgYFkVFvUOYaeJ46pCzfOA_k-zfM62blkGup1_De4DvB7S_S3t7kdY7W57s4vAp5N7TvEfAH7S-v4 |
| link.rule.ids | 315,783,787,2772,27088,27936,27937,57066,57116 |
| linkProvider | American Chemical Society |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV1Jb9QwFH6CcigX9iWUthbqAQ5p62yOj1GGaoBODtBKvUXeUkbQBDXJpRf-ep-dZDpAJXqzvMXLs9_nvOfPAHvGcMOZSPyk4tyPYkb9lCrpIzZG9WviKnQkSYsimZ9Gn8_is5Emx96FwUa0WFPrjPg37AL0oPlpqUOS5Pw-PIgZBiwMyr-tLAaoh7jjRg1C3zLCTCxC60WtBlLtnxroH1h5qwZy2ubo8fBskWunczL5sd93cl9d_UXheLeOPIFHI-gk2SAlT-GeqZ_BZj699fYcfs8mrxg7T6SpSCadUBpirwQuz_tBUFqXdGFd5YmotQs2JFNL3RLnfECKplbfl5f4tRnKtv3fe2WjM3uDqyXvi3yWfXBFZ8Y-JrHsL0ix-PoCTo8-nuRzf3yawRchpZ3PIi0RWcU6qhiTaShCTkPGVaAlTQxPja7UIVcC0ZKMRMxwe8dIIbTRhzKpgvAlbNRNbV4D0ZE9YvK4QiwaSRoLzpTiUSWMTnE7UR7s4DCW49JqS2c1D2i5GkcP3k3zWf4aKDpuy7Q7zXSJY2utIqI2Td-WLAgQY9HYg1eDAKxVgodHBJQe7K1LxCrd4e00ccxVKIAe0Ltky0fudcs50L35X-d2YXN-sjgujz8VX7bg4UAEYAl538JGd9mbbYREndxxa-EaHSkDcg |
| linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV1Jb9UwEB5BkYAL-xKW1kI9wCFtnd3HKOGpLA0IqNRb5LU8tU2qJrn0wl9n7CRPD6hEb5G3eBl7PnvGnwG2tWaapTzxE8OYH8Up9TMqhY_YGNWvjk3oSJIOqmT_MPp4FB9NG0V7FwYr0WFJnTPi21l9rszEMEB321NLH5IkxzfhFpbqzLJ58X1lNUBdxBw_ahD6lhVmZhJaz2q1kOz-1EL_QMsrtZDTOIv78GVVV-docrIz9GJHXv5F43j9xjyAexP4JPkoLQ_hhm4ewZ1ifvPtMfwqZ-8YO16kNSQXTjg1sVcDl8fDKDCdizqzLvOEN8p9tiSXS9UR54RAqraRP5cX-LcSZdye-17a4Nze5OrI26oo83cua6ntoxLL4YxUB9-ewOHi_Y9i35-eaPB5SGnvp5ESiLBiFZk0FVnIQ0bDlMlACZpolmll5B6THFGTiHic4jKPgZwrrfZEYoLwKWw0baOfA1GR3Wqy2CAmjQSNOUulZJHhWmW4rEgPNrEr62mKdbWznge0XvWjB2_mMa3PR6qOqxJtzaNdY99a6whvdDt0dRoEiLVo7MGzUQjWCsFNJAJLD7bXpWIV73B3ljgGKxRCD-h1khUTB7vlHuhf_K9xW3D7a7moP3-oPr2EuyMfgOXlfQUb_cWgXyMy6sWmmw6_AXubBew |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Determination+of+Absolute+Configurations+of+Amines+and+Amino+Acids+Using+Nonchiral+Derivatizing+Agents+%28NCDA%29+and+Deuterium+NMR&rft.jtitle=Organic+letters&rft.au=Chalard%2C+Pierre&rft.au=Bertrand%2C+Magali&rft.au=Canet%2C+Isabelle&rft.au=Th%C3%A9ry%2C+Vincent&rft.date=2000-08-10&rft.issn=1523-7060&rft.eissn=1523-7052&rft.volume=2&rft.issue=16&rft.spage=2431&rft.epage=2434&rft_id=info:doi/10.1021%2Fol006066g&rft.externalDBID=n%2Fa&rft.externalDocID=10_1021_ol006066g |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1523-7060&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1523-7060&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1523-7060&client=summon |