Serum from normal elderly individuals contains anti-basement membrane zone antibodies

• Published in: Archives of dermatology (1960) Vol. 132; no. 10; p. 1201
• Main Authors: Hachisuka, H, Kurose, K, Karashima, T, Mori, O, Maeyama, Y
• Format: Journal Article
• Language: English
• Published: United States 01.10.1996
• Subjects: Adult; Aged; Aged, 80 and over; Aging - immunology; Animals; Autoantibodies - analysis; Basement Membrane - immunology; Fluorescent Antibody Technique, Direct; Fluorescent Antibody Technique, Indirect; Guinea Pigs; Humans; Middle Aged; Pemphigoid, Bullous - immunology; Reference Values

Bullous pemphigoid is an autoimmune bullous disease with circulating anti-basement membrane zone antibodies, and it commonly affects elderly individuals; however, the reasons for the late onset of the disease are unclear. The anti-basement membrane zone antibodies in serum samples from normal elderl...