Photoimmunotherapy-Induced Pyroptosis Remodels the Microenvironment to Enhance Cancer Immunotherapy

• Published in: ACS materials letters Vol. 6; no. 8; pp. 3750 - 3762
• Main Authors: Zhang, Wenqiao, Yuan, Haitao, Wang, Peili, Yi, Letai, Wen, Qinglian, Zhou, Runhua, Bai, Yunmeng, Ma, Jingbo, Wang, Xiaoxian, Liang, Yanting, Liang, Zhen, Peng, Xin, Wang, Jigang, Xiao, Wei
• Format: Journal Article
• Language: English
• Published: American Chemical Society 05.08.2024

Immunosuppressive tumor microenvironment (TME) and immune escape are the main reasons that make immunotherapy ineffective and even hinder tumor progression. Immunogenic cell death (ICD) based on pyroptosis stands up as an ideal strategy to overcome the TME and achieve satisfactory antitumor effects....