Triglyceride-Tethered Membrane Lipase Sensor

• Published in: ACS applied materials & interfaces Vol. 15; no. 45; pp. 52237 - 52243
• Main Authors: Lankage, Upeksha Mirissa, Holt, Stephen A., Bridge, Samara, Cornell, Bruce, Cranfield, Charles G.
• Format: Journal Article
• Language: English
• Published: American Chemical Society 06.11.2023
• Subjects: Biological and Medical Applications of Materials and Interfaces; triolein; tethered lipid membranes; lipase sensor; electrical impedance spectroscopy (EIS); neutron reflectometry

Sensors that can quickly measure the lipase activity from biological samples are useful in enzyme production and medical diagnostics. However, current lipase sensors have limitations such as requiring fluorescent labels, pH control of buffer vehicles, or lengthy assay preparation. We introduce a spa...