Radiosynthesis, In Vitro Characterization, and In Vivo PET Neuroimaging of [18F]F‑4 for Tau Protein: A First-in-Human PET Study - Lindberg, Anton; Tong, Junchao; Zheng, Chao; Mueller, Andre; Kroth, Heiko; Stephens, Andrew; Mathis, Chester A.; Vasdev, Neil (ACS chemical neuroscience, 2025)
Keywords: Alzheimer Disease - diagnostic imaging; Alzheimer Disease - metabolism; Animals; Brain - diagnostic imaging; Brain - metabolism; Female; Fluorine Radioisotopes; Humans; Male; Neuroimaging - methods; Positron-Emission Tomography - methods; Radiopharmaceuticals - chemical synthesis; Radiopharmaceuticals - pharmacokinetics; Rats; Supranuclear Palsy, Progressive - diagnostic imaging; Supranuclear Palsy, Progressive - metabolism; tau Proteins - metabolism; Tauopathies - diagnostic imaging; Tauopathies - metabolism; tau; fluorine-18; [18F]PI-2620; positron emission tomography; [18F]F-4