Naloxone and Patient Outcomes in Out-of-Hospital Cardiac Arrests in California

• Published in: JAMA network open Vol. 7; no. 8; p. e2429154
• Main Authors: Dillon, David G, Montoy, Juan Carlos C, Nishijima, Daniel K, Niederberger, Sara, Menegazzi, James J, Lacocque, Jeremy, Rodriguez, Robert M, Wang, Ralph C
• Format: Journal Article
• Language: English
• Published: United States American Medical Association 01.08.2024
• Subjects: Adult; Aged; California - epidemiology; Cardiac arrest; Cardiopulmonary Resuscitation - methods; Cardiopulmonary Resuscitation - statistics & numerical data; Cohort analysis; Emergency Medical Services - statistics & numerical data; Emergency Medicine; Female; Humans; Male; Middle Aged; Naloxone - therapeutic use; Narcotic Antagonists - therapeutic use; Online Only; Original Investigation; Out-of-Hospital Cardiac Arrest - drug therapy; Out-of-Hospital Cardiac Arrest - epidemiology; Out-of-Hospital Cardiac Arrest - mortality; Patients; Retrospective Studies; Treatment Outcome; California

The incidence of opioid-associated out-of-hospital cardiac arrest (OA-OHCA) has grown from less than 1% of OHCA in 2000 to between 7% and 14% of OHCA in recent years; American Heart Association (AHA) protocols suggest that emergency medical service (EMS) clinicians consider naloxone in OA-OHCA. Howe...