Mechanistic Insights into Paracetamol Crystallization: Exploring Ultrasound and Hydrodynamic Cavitation with Quartz Crystal Microbalance Dissipation

• Published in: ACS Engineering Au Vol. 5; no. 1; pp. 36 - 44
• Main Authors: Dhanasekaran, Madhumitha, Sarvothaman, Varaha P., Guida, Paolo, Roberts, William L.
• Format: Journal Article
• Language: English
• Published: American Chemical Society 19.02.2025
• Subjects: crystallization; quartz crystal microbalance (QCM-D); paracetamol; hydrodynamic cavitation; ultrasound cavitation

Crystallization is a crucial process in the purification of active pharmaceutical ingredients (APIs). Achieving controlled and efficient crystal formation is vital in successful production for industrial applications. This study investigates the crystallization of paracetamol using a model system, f...