Kinetic Model for the Reversible Hydration of Carbon Dioxide Catalyzed by Human Carbonic Anhydrase II

• Published in: Industrial & engineering chemistry research Vol. 49; no. 19; pp. 9095 - 9104
• Main Author: Larachi, F
• Format: Journal Article
• Language: English
• Published: Washington, DC American Chemical Society 06.10.2010
• Subjects: Applied sciences; Catalysis; Catalytic reactions; Chemical engineering; Chemistry; Exact sciences and technology; General and physical chemistry; Kinetics, Catalysis, and Reaction Engineering; Reactors; Theory of reactions, general kinetics. Catalysis. Nomenclature, chemical documentation, computer chemistry; Human; Kinetic model; Catalytic reaction; Hydration; Modeling; Carbon dioxide

Four variants of the two-step Ping Pong mechanism for the reversible hydration of carbon dioxide to bicarbonate catalyzed by free human carbonic anhydrase II (HCA II) in solutions were derived and their goodness-of-fit to match measured initial hydration rates tested. The pseudo (i.e., no central co...