Structure and Phase Transitions of Genipin, An Herbal Medicine and Naturally Occurring Cross-Linker

• Published in: Crystal growth & design Vol. 8; no. 5; pp. 1748 - 1753
• Main Authors: Trevor, Susannah L, Butler, Micheal F, Adams, Sarah, Laity, Peter R, Burley, Jonathan C, Cameron, Ruth E
• Format: Journal Article
• Language: English
• Published: Washington,DC American Chemical Society 01.05.2008
• Subjects: Condensed matter: structure, mechanical and thermal properties; Cross-disciplinary physics: materials science; rheology; Equations of state, phase equilibria, and phase transitions; Exact sciences and technology; Growth from solutions; Materials science; Methods of crystal growth; physics of crystal growth; Organic compounds; Physics; Solid-solid transitions; Specific phase transitions; Structure of solids and liquids; crystallography; Structure of specific crystalline solids; Drugs; Differential scanning calorimetry; Specimen preparation; Phase transformations; Crystallization; Polymerization; XRD; Evaporation; Monoclinic lattices; Phase transitions; Genipin; Monocrystals; Cross-linking; Crystal growth from solutions; Hydrogel; Thermodynamic properties; Synchrotron radiation; Methanol; Crystal structure

The naturally occurring cross-linking agent genipin has recently been the subject of biomedical research both in the creation of hydrogel structures and as a potential active agent in its own right. In this study several methods of specimen preparation were used to isolate and stabilize crystalline...