Differential Partitioning of Bioantioxidants in Edible Oil–Water and Octanol–Water Systems: Linear Free Energy Relationships
Partition coefficients, P W O, of antioxidants (AOs) between edible oils and water are scarce in the literature, despite that AOs are widely used to control lipid oxidation and the oxidative stress in cells. P W O values have a great importance to predict the efficiency and distribution of bioactive...
Saved in:
Published in | Journal of chemical and engineering data Vol. 63; no. 8; pp. 2999 - 3007 |
---|---|
Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
American Chemical Society
09.08.2018
|
Online Access | Get full text |
Cover
Loading…
Summary: | Partition coefficients, P W O, of antioxidants (AOs) between edible oils and water are scarce in the literature, despite that AOs are widely used to control lipid oxidation and the oxidative stress in cells. P W O values have a great importance to predict the efficiency and distribution of bioactives at different levels of biological organization from binary oil–water systems to living cells. Here, we determined the partition coefficients, P W O, of four series of potent, natural AOs of increasing lipophilicity between vegetable oils (olive, soybean, and corn) and water and, for the sake of comparison, between octanol–water, P W OCT. Results indicate that the contribution of the −CH2 groups to the overall lipophilicity of the AO is the same irrespective of the oil employed. The P W O values were compared with P W OCT values, and linear relationships were obtained for each series of AOs. Results indicate that, in general, P W O values cannot be predicted from the P W OCT values, making necessary to determine the P W O values for each oil and antioxidant. |
---|---|
ISSN: | 0021-9568 1520-5134 |
DOI: | 10.1021/acs.jced.8b00258 |